Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue
Robert Tycko and colleagues find that amyloid fibrils derived from AD patient brain tissue reveal a single predominant structure within a patient sample but with key differences between samples, raisi...
Endoderm Formation: Not So Black and White Anymore
Endoderm Formation: Not So Black and White Anymore - Dr. Hadjantonakis discusses the work of her group on using live-imaging approaches coupled with genetic labeling in the mouse embryo to uncover the...
Previous genome-wide association studies identified CD33 as a Alzheimer's disease risk gene. Through examination of human samples and mouse models of Alzheimer's disease, Griciuc et al. uncover a nove...
Bruchpilot Acetylation Influences Active Zone Structure
Bruchpilot Acetylation Influences Active Zone Structure - Patrik Verstreken and co-authors find that in addition to acetylating histones in the nucleus, the histone acetyl-transferase ELP3 plays a rol...
Amygdala Predicts Stress Vulnerability - This video summarizes the results of a Duke University study finding that higher amygdala reactivity to threat predicts greater symptoms of anxiety and depress...
Human Mutation - Kakkhee Yeung "Transdifferentiation of Human Dermal Fibroblasts to Smooth Muscle-Like Cells to Study the Effect of MYH11 and ACTA2 Mutations in Aortic Aneurysms"...
The Neurobiology of Gendered Behavior. Catherine Dulac speaks about “The Neurobiology of Gendered Behavior” at the Cell Press/AWIS LabLinks meeting on The Gender of Science and the Science of Gender h...
Assembly and budding of a virus from a membrane microdomain
Assembly and Budding of a Virus from a Membrane Microdomain - Viruses have an outer protein shell (called a capsid) that surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an addit...
Visual control of octopus arm movements - Octopuses are known among invertebrates for their sophisticated behavior and the task they face of controlling eight flexible arms is a daunting one. As expla...