BRCA2 Bandages Stalled Forks - Maria Jasin and Katharina Schlacher reveal a new function for the breast cancer tumor suppressor BRCA2: in addition to repairing DNA damage, it prevents breaks from occu...
Sex and the Struggle for Existence - David Clapham speaks about “Sex and the Struggle for Existence” at the Cell Press/AWIS LabLinks meeting on The Gender of Science and the Science of Gender held on ...
When the Break Is Just around the Loop/ Cell, July 27, 2017 (Vol. 170, Issue 3)
When the Break Is Just around the Loop. Inside the nucleus, DNA is packed in highly complex structures that help to control which genes are on and off each time. In this video abstract, Andre Nussenzw...
Ocean 180 - The Harp Sponge: An extraordinary new species of carnivorous sponge. n this video we describe a new species of carnivorous sponge, Chondrocladia lyra from the deep-sea off California. It i...
A New Strategy for Treating Neuropathic Pain - Conventional methods of pain treatment have often proved ineffective in the treatment of neuropathic pain. Here, in an effort to develop a new therapeuti...
Evolutionary Divergence in the Hedgehog Pathway - Drs. Toftgård, Teglund, and Heby-Henricson offer a personal account of the work published in this paper and highlight areas of current research on the...
The Temporal Sequence of the Mammalian Neocortical Neurogenetic Program Drives Mediolateral Pattern in the Chick Pallium. The six-layered neocortex permits complex information processing in all mammal...
Cues for Synapse Formation - The external cues that dictate synapse assembly are not well understood. Watch David Ginty and colleagues describe their findings that NGF plays a critical role in determi...
Watching Inhibitory Synapses Remodel - By simultaneously monitoring in vivo synapse and dendritic spine dynamics in adult mammalian cortical pyramidal cells, Elly Nedivi and colleagues provide new ins...
Orchestrated amplification and differentiation of intermediate progenitors governs the evolutionary expansion of the cerebral cortex. Fang et al. report that Axin serves as a master scaffold that dete...
Establishing Robust Left-Right Asymmetry in the Vertebrate Embryo
Establishing Robust Left-Right Asymmetry in the Vertebrate Embryo - Tetsuya Nakamura discusses the role of a Nodal-Lefty-based reaction-diffusion system in generating left-right asymmetry in the mouse...