An ERC research project led by Prof. Michael Boutros (DKFZ and Heidelberg University) analyzes genetic interactions in living cells with high-thoughput technology such as robotics and automatic micros...
Removing Stressed Mitochondria from Axons Independent of Mitophagy
Removing Stressed Mitochondria from Axons Independent of Mitophagy. Lin and Cheng et al. reveal a new mechanism maintaining axonal mitochondrial integrity by releasing anchoring protein syntaphilin fr...
Feedback Control of Vocal Learning - During vocal learning, the ear monitors and instructs the voice. Lei & Mooney examine where auditory feedback processed in the brain and how it modifies motor...
Where and How Is Motor Memory Stored?/Cell October 27, 2016 (Vol. 167, Issue 4)
Where and How Is Motor Memory Stored?/Cell October 27, 2016 (Vol. 167, Issue 4) - Have you ever wondered why you lost appetite when sick? Maybe it is your body's way to tell you not to eat certain foo...
miRNA, Notch, and Amygdala-Dependent Fear Learning
In this video, Dias et al. summarize data that shows that a microRNA in the amygdala (miR-34a) regulates Notch signaling after auditory fear conditioning. Their work makes a case for this interaction ...
Aneuploidy via Telomere Attrition - Telomere dysfunction and aneuploidy are both common features of cancer cells. But are they causally linked? Watch and listen as Titia de Lange and Teresa Davoli tak...
Simulation of the Clock and Wavefront Mechanism - The segmentation clock is modeled here as a population of oscillating cells, whose cyclic gene expression phase is represented in blue in the posterio...
Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging
Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging - Vittorio Sartorelli and Marcella Fulco discuss their identification of a nutrient-sensing pathway that governs the differentiat...
This video shows the cross-sectional two-photon microscopy of normal embryos. This is an example of lateral tissue lengthening and shortening in a living embryo....
Exploring Astrocyte Diversity in Neural Circuits. Chai, Díaz-Castro et al. briefly highlight methods used to explore astrocytes in the hippocampus and striatum. The data show that astrocytes are disti...
Human Mutation - Yuehua Zhang, Liping Wei, and colleagues
Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo” SCN1A Mutations in Children with Dravet Syndrome. The majority of children with Dravet syndrome (DS) are caused b...
TIBS Science & Society: Multimedia for grant applications
Multimedia: a necessary step in the evolution of research funding applications by and featuring authors Mike Doran and Bill Lott.Multimedia communication capabilities are rapidly expanding, and visual...
Blebs on the Move - Erez Raz and his colleagues use a tour through their lab to walk you through the approach they took to analyzing the migratory behavior of primordial germ cells in vivo....
