The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation

Ron Germain and colleagues identify the mitochondrial adapter molecule MAVS as a critical regulator of inflammasome activation. They discuss their findings on how MAVS and another adapter, ASC, are bo...

When the Break Is Just around the Loop/ Cell, July 27, 2017 (Vol. 170, Issue 3)

When the Break Is Just around the Loop. Inside the nucleus, DNA is packed in highly complex structures that help to control which genes are on and off each time. In this video abstract, Andre Nussenzw...

Looking Deep: Rise of the Machines / Cell, February 22, 2018 (Vol. 172, Issue 5)

(1) Looking Deep: Rise of the Machines / Cell, February 22, 2018 (Vol. 172, Issue 5)...

Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging

Connecting the Dots: Linking Sirtuins and AMPK in Metabolism and Aging - Vittorio Sartorelli and Marcella Fulco discuss their identification of a nutrient-sensing pathway that governs the differentiat...

"Christmas Tree Worms" | California Academy of Sciences

"Christmas Tree Worms" | California Academy of Sciences - YouTube...

Imperfect Mimics Can Succeed as Long as They Mimic the Most Salient Trait

There are many surprising examples of imperfect mimicry in nature, and their existence remains a major unsolved conundrum. Kazemi et al. present a novel explanation of the phenomenon and test it with ...

Circuit for Arousal from Sleep during Hypercapnia

Circuit for Arousal from Sleep during Hypercapnia ...

PARP around the Clock

PARP around the Clock - Circadian rhythms are entrained with feeding schedules. Watch as Gad Asher takes you on a brief, personally guided tour of his discovery that nutrient intake regulates the osci...

Figure360: Trends in Plant Science, Sun, Baudino, and colleagues, Figure 2

Figure360: Trends in Plant Science, Sun, Baudino, and colleagues, Figure 2 - YouTube...

Phospholipid Enters Receptor's G-Protein Binding Site

Phospholipid Enters Receptor's G-Protein Binding Site - A phospholipid from the membrane's cytosolic leaflet (yellow) enters the empty G-protein binding site of an activated beta 2 adrenergic receptor...

Feeding despite Immediate Metabolic Need

Feeding despite Immediate Metabolic Need - Christian Lüscher and Eoin O’Connor describe research that has investigated the role of inhibitory output from the nucleus accumbens shell to the lateral hyp...

V1 Neuronal Population Responses to Oriented Grating Stimuli

V1 Neuronal Population Responses to Oriented Grating Stimuli ...

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

Florian Greten and colleagues explain why enhanced Wnt signaling causes postmitotic (non-stem) cells to dedifferentiate and reacquire stem cell characteristics, enabling the cells to initiate tumorige...

Figure360: Trends in Cancer, Tauriello & Batlle, Figure 1

Figure360: Trends in Cancer, Tauriello & Batlle, Figure 1 - YouTube...

How microtubules affect the shape of the endoplasmic reticulum

How microtubules affect the shape of the endoplasmic reticulum...

Brain Shuttle Transports Antibodies into the Brain over the Blood-Brain Barrier

Roche has developed a novel Brain Shuttle technology that transporst antibodies across the blood-brain barrier. This technology has the potential to be used to treat numerous brain diseases. For more ...

Endoderm Formation: Not So Black and White Anymore

Endoderm Formation: Not So Black and White Anymore - Dr. Hadjantonakis discusses the work of her group on using live-imaging approaches coupled with genetic labeling in the mouse embryo to uncover the...

Getting Paid What You're Worth

Getting Paid What You're Worth. Evelyn Murphy speaks about “How to get paid what you’re worth” at the Cell Press/AWIS LabLinks meeting on The Gender of Science and the Science of Gender held on Thursd...

Jack Dumbacher: Local Guides Out in the Field | California Academy of Sciences

Jack Dumbacher: Local Guides Out in the Field | California Academy of Sciences - YouTube...

Control of Transient Genomic Instability / Cell, August 9, 2018 (Vol. 174, iss. 4)

(4) Control of Transient Genomic Instability / Cell, August 9, 2018 (Vol. 174, iss. 4) ...