Training Away Distractibility - Jyoti Mishra & Adam Gazzaley at UCSF discuss the motivation, approach, findings, applications, and broader implications of their new study published in Neuron, &quo...
Evolving Roles for Inhibitory Interneurons in Seizures
Evolving Roles for Inhibitory Interneurons in Seizures. Using a combination of optogenetics and calcium imaging, Khoshkhoo et al. show how various classes of interneurons play distinct and evolving ro...
BRCA2 Bandages Stalled Forks - Maria Jasin and Katharina Schlacher reveal a new function for the breast cancer tumor suppressor BRCA2: in addition to repairing DNA damage, it prevents breaks from occu...
PARP around the Clock - Circadian rhythms are entrained with feeding schedules. Watch as Gad Asher takes you on a brief, personally guided tour of his discovery that nutrient intake regulates the osci...
Assembly and budding of a virus from a membrane microdomain
Assembly and Budding of a Virus from a Membrane Microdomain - Viruses have an outer protein shell (called a capsid) that surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an addit...
Matthew Tyska and colleagues find that intestinal microvilli assemble in the form of clusters that are linked together at the tips by cadherin family proteins....
NMDA Receptor Signaling Critical for Habit Formation
NMDA Receptor Signaling Critical for Habit Formation - How does the brain form habits? Joe Tsien and colleagues explore the cellular mechanisms underlying habit formation and find that NMDA receptors ...
V2 in Motion Perception - Motion perception is thought to be mediated by the dorsal visual pathways. In this video abstract, Anna Roe and colleagues discuss their data demonstrating that V2 is also in...
Computational Neuropsychiatry - Whole-brain computational models can help generate and predict the dynamical interactions and consequences of brain networks over many timescales in both health and dis...
Video Abstract: "Species Delimitation and Global Biosecurity"
In this video abstract, Dr Laura Boykin speaks about her article "Species Delimitation and Global Biosecurity", recently published in Evolutionary Bioinformatics. This is an open access arti...
Clock and Wavefront Model for Vertebrate Segmentation
Clock and Wavefront Model for Vertebrate Segmentation - This model proposes that the production of somites during embryogenesis results from a molecular oscillator (called the clock) traveling along t...
The scent of danger: A 70-year-old puzzle solved - When injured, many freshwater fish release an alarm substance that triggers fear in other members of their school. This substance, which is found in ...
Turning to the Light - In Arabidopsis, light induces the translocation of phytochrome photoreceptors from the cytoplasm to subnuclear compartment called phytochrome nuclear bodies. Watch and listen as...