Differential Hippo Signaling in Early Mouse Embryos
Differential Hippo Signaling in Early Mouse Embryos - Hiroshi Sasaki discusses his group's recent findings on the role of differential Hippo signaling in regulating cell fate during trophectoderm form...
Snakes on the DNA Plane - How can protein complexes slide along DNA while still remaining wrapped up in its strands? Using optical tweezers and a baseball, Taekjip Ha and Ruobo Zhou show us how in thi...
CONVERSATIONS IN THE BRAIN: How neural progenitor cells control their own fate
Neurogenesis relies on a delicate balance between progenitor maintenance and neuronal production. Oscar Marin and colleagues find that the Robo1 and Robo2 receptors and their Slit protein ligands, kno...
Cellular and Molecular Mechanisms of Peripheral Nerve Regeneration
Cellular and molecular mechanisms of peripheral nerve regeneration - In this video abstract, the authors use the in vivo imaging to examine if and how regenerating axons return to their original targe...
Light, both natural and artificial, is a powerful cue for the circadian clock, the internal timing device that tells us when to wake up and go to sleep, when to eat, and when we are most mentally aler...
What Makes an Osteoclast Special? - Hiroshi Takayanagi, discusses how he decided at the time to investigate the transcriptional effectors of osteoclast RANKL signaling, within Tadatsugu Taniguchi's gr...
Bidirectional Transcription and Antisense Repression of ataxin-7
Bidirectional Transcription and Antisense Repression of ataxin-7 - CAG repeat expansions in the ataxin-7 gene cause the neurodegenerative disorder SCA7. Al La Spada and colleagues have discovered tha...
Obtaining a clear picture of the proteins that interact with the Huntingtin protein will provide clues for the development of Huntington's disease therapies. In this study, William Yang and colleagues...
How do oil and other toxins move from deep water onto the beach? Using dye and drones, a team of scientists conduct a series of experiments to explore how ocean currents transport material from offsho...
Brain-Machine Interfaces: Combining Decoder Design and Neural Adaptation
Brain-Machine Interfaces: Combining Decoder Design and Neural Adaptation - Shenoy and Carmena introduce the concept of a brain-machine interface, how to design a decoder algorithm to convert neural ac...
Wnts come in small packages - Wnts are signaling molecules important for development and neuronal functions. Watch and listen as Vivian Budnik and her colleagues take you on a brief personally guided...
De Novo Coding Variants Are Strongly Associated With Tourette Disorder
De Novo Coding Variants Are Strongly Associated With Tourette Disorder. New research led by UC San Francisco scientists Jeremy Willsey and Matthew State has identified four likely risk genes with mult...
Bruchpilot Acetylation Influences Active Zone Structure
Bruchpilot Acetylation Influences Active Zone Structure - Patrik Verstreken and co-authors find that in addition to acetylating histones in the nucleus, the histone acetyl-transferase ELP3 plays a rol...
Gender + Science: Conquering Bias Together. Anne Deconinck speaks about “Conquering Bias Together” at the Cell Press/AWIS LabLinks meeting on The Gender of Science and the Science of Gender held on Th...
A New Exit from the Nucleus - RNP granules bud through the nuclear envelope, finds Vivian Budnik, providing a route to the cytosol that bypasses the pore....
