Activating Genius; Lesson 1 Neurogenesis

Orchestrated amplification and differentiation of intermediate progenitors governs the evolutionary expansion of the cerebral cortex. Fang et al. report that Axin serves as a master scaffold that dete...

Left Habenula Mediates Light-Preference Behavior

Left Habenula Mediates Light-Preference Behavior in Zebrafish via an Asymmetrical Visual Pathway. Habenula (Hb) plays critical roles in emotion-related behaviors through integrating inputs mainly from...

Sortilin Link to Dementia Pathophysiology

Sortilin Link to Dementia Pathophysiology - Mutation of the gene for PGRN causes Fronto-Temporal Lobar Degeneration but the mechanistic link between reduced PRGN levels and neurodegeneration is unknow...

Mutations in GlialCAM Can Cause the Leukodystrophy MLC

Mutations in GlialCAM Can Cause the Leukodystrophy MLC - Mutations in the cell adhesion molecule GlialCAM can cause the leukodystrophy MLC. Raul Estevez and colleagues find that GlialCAM acts as an au...

Developmental Cell Burkel/Bement video abstract

The non-imaging-forming visual system has important physiological roles, including entrainment of the circadian rhythm, but its development is not well understood. Here, Andrew Lumsden and colleagues ...

Connections in a Cube/ Cell, July 30, 2015 (Vol. 162, Issue 3)

Connections in a Cube/ Cell, July 30, 2015 (Vol. 162, Issue 3) - YouTube...

Human Mutation - Brianne Kirkpatrick and colleagues

Authors, Brianne Kirkpatrick and colleagues, on their published paper in Human Mutation entitled "GenomeConnect: Matchmaking Between Patients, Clinical Laboratories, and Researchers to Improve Ge...

Chimp Tool Use in Budongo Forest: The Sonso Community

Chimp Tool Use in Budongo Forest: The Sonso Community ...

Developmental Cell Roostalu/Strähle video abstract

Developmental Cell Journal -- Roostalu and Strähle video abstract...

Watch It Grow!

Watch It Grow! ...

Portabella: A New Player in Neurotransmission

Portabella: A New Player in Neurotransmission - David Krantz and colleagues report the discovery of portabella, a Drosophila gene that is structurally similar to known vesicular transporters and is ex...

Episodic-like Memory in Dogs Revealed by Do As I Do/ Curr. Biol., Dec. 5, 2016 (Vol. 26, Issue 23)

Episodic-like Memory in Dogs Revealed by Do As I Do/ Curr. Biol., Dec. 5, 2016 (Vol. 26, Issue 23) - This video abstract illustrates how episodic-like memory of incidentally encoded complex events was...

Protein Aggregation Up-Close/ Cell Sept. 21, 2017 (Vol. 171, No. 1)

Protein Aggregation Up-Close/ Cell Sept. 21, 2017 (Vol. 171, No. 1) ...

Cingulate-Hippocampus Coordination Regulates Choice Coding

This video shows rats choosing sequentially from four distinct trajectories in a maze while we record neural activity from hippocampus and cingulate cortex. Analyses of such neural activity led us to ...

Cell Surface Topography Is a Regulator of Molecular Interactions

A neutrophil labeled with Alexa-488-conjugated anti-L-selectin spreads onto and engulfs an IL-8-coated glass bead in bright field, epifluorescence, and TIRFM. See the paper by Lomakina et al. in the S...

How chimpanzees handle death: Biro, part 2

How chimpanzees handle death: Biro, part 2 ...

Wild capuchins use stone tools

Wild capuchins use stone tools ...

Cascade Defense Tactics/Cell, Oct. 29, 2015 (Vol. 163, Issue 4)

Cascade Defense Tactics/Cell, Oct. 29, 2015 (Vol. 163, Issue 4) - CRISPR defends bacteria against viral invasion by recognizing the viral DNA sequence. What if virus mutates the sequence? The paper by...

A Journey Into Entorhinal Cortex | Edvard and May-Britt Moser | NTNU

Kimberly Stroka and colleagues describe a propulsion mechanism for cancer cells that relies on a spatial gradient of channels and pumps in the plasma membrane, rather than acto-mysosin contractility....

Cellular and Molecular Mechanisms of Peripheral Nerve Regeneration

Cellular and molecular mechanisms of peripheral nerve regeneration - In this video abstract, the authors use the in vivo imaging to examine if and how regenerating axons return to their original targe...