miRNA, Notch, and Amygdala-Dependent Fear Learning
In this video, Dias et al. summarize data that shows that a microRNA in the amygdala (miR-34a) regulates Notch signaling after auditory fear conditioning. Their work makes a case for this interaction ...
p53's Hit Men - p53 both activates and represses gene expression to defend against tumorigenesis. Watch and listen as John Rinn takes you on a brief, personally guided tour of his lab's findings that ...
The Temporal Sequence of the Mammalian Neocortical Neurogenetic Program Drives Mediolateral Pattern in the Chick Pallium. The six-layered neocortex permits complex information processing in all mammal...
Neocortex Recycles Olfactory Cajal-Retzius Cells - The neocortex undergoes extensive developmental growth, but how its architecture adapts to expansion remains largely unknown. Here, we investigated h...
In this video, Ira Espuny-Camacho and Pierre Vanderhaeghen describe how human pluripotent stem cells can be turned into cortical pyramidal neurons, mimicking key aspects of human corticogenesis. Most ...
In A Flash: Firefly Communication - Fireflies communicate with a "language of light" that scientists still don't completely understand. James Lloyd and Marc Branham of the University of Flor...
Turning to the Light - In Arabidopsis, light induces the translocation of phytochrome photoreceptors from the cytoplasm to subnuclear compartment called phytochrome nuclear bodies. Watch and listen as...
Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes
Orbitofrontal Cortex: Prediction and Evaluation of Behavioral Outcomes - The orbitofrontal cortex has long been associated with concepts like impulsivity, self-control, and emotion regulation. Here we...
Fear Signals from Predators - Mice exhibit fear behavior towards predators, or simply predator odors, even without prior exposure to these predators. Watch and listen as Lisa Stowers and Fabio Papes t...
Synapse Number Regulates Alcohol Sensitivity - Alcohol-related problems are associated with reduced sensitivity to alcohol. Eddison et al. find that arouser (aru), a predicted adaptor protein, functio...