How to Undress an mRNP

How to Undress an mRNP - Nonsense-mediated mRNA decay requires the RNA helicase Upf1, but as Jens Lykke-Andersen and colleagues explain, Upf1 does more than unwind RNA. It also strips off the mRNA's p...

Ferroptosis: A New Type of Programmed Cell Death

Ferroptosis: A New Type of Programmed Cell Death - Distinct from apoptosis, necrosis, and autophagy, "iron-dependent cell death" emerged while Brent Stockwell and his lab were investigating ...

A New Strategy for Treating Neuropathic Pain

A New Strategy for Treating Neuropathic Pain - Conventional methods of pain treatment have often proved ineffective in the treatment of neuropathic pain. Here, in an effort to develop a new therapeuti...

Human Mutation - Kakkhee Yeung

Human Mutation - Kakkhee Yeung "Transdifferentiation of Human Dermal Fibroblasts to Smooth Muscle-Like Cells to Study the Effect of MYH11 and ACTA2 Mutations in Aortic Aneurysms"...

Mitochondrial links to genomic instability in aging

Mitochondrial links to genomic instability in aging - Understanding why our genomes become more prone to mutations as we age is a key goal of ageing and cancer research. Dr. Dan Gottschling and his co...

Coordinated Nose, Head, and Vibrissa Motion in Rats/ Curr. Biol., Feb. 16, 2017 (Vol. 27, Issue 5)

Coordinated Nose, Head, and Vibrissa Motion in Rats/ Curr. Biol., Kurnikova et al. examine orofacial movements in rats, which include nose orienting, head bobbing, and whisking. This video demonstrate...

Postinvasion reactivation of the Shigella flexneri

Postinvasion reactivation of the Shigella flexneri ...

V1 Neuronal Population Responses to Oriented Grating Stimuli

V1 Neuronal Population Responses to Oriented Grating Stimuli ...

When Genetic Instability Is a Good Thing

When Genetic Instability Is a Good Thing - Dr. Orr-Weaver discusses her group's work on regulatory programs that amplify (or suppress) overreplication of cell-type-appropriate genes in the Drosophila ...

Confocal time lapse imaging of a developing kidney

(1) Confocal time lapse imaging of a developing kidney ...

Single-Neuron Integration of Plasticity Mechanisms Actuates a Memory

Single-Neuron Integration of Plasticity Mechanisms Actuates a Memory - YouTube...

A neuronal channel protein controls planarian movement

A neuronal channel protein controls planarian movement ...

Hitting on the Causes of Diabetes / Cell, June 29, 2017 (Vol. 170, Issue 1)

Hitting on the Causes of Diabetes / Cell, June 29, 2017 (Vol. 170, Issue 1) -...

TiBS Review Protein mistranslation: Friend or foe?

Read the full article here: http://bit.ly/1oGNRdF The translation of genes into functional proteins is not error-free. Incorporation of the wrong amino acids, known as mistranslation, can cause disea...

Baillie Redfern - Video Abstract - Poster Presentation - Genomics: The Power and the Promise

Baillie Redfern, UBC, discusses her research "Engineering the production of isoprenoids from Abies balsamea in a biological host system" at the Genomics: The Power and The Promise (November ...

RNA Processing RNA

RNA Processing RNA ...

Activating Genius; Lesson 1 Neurogenesis

Orchestrated amplification and differentiation of intermediate progenitors governs the evolutionary expansion of the cerebral cortex. Fang et al. report that Axin serves as a master scaffold that dete...

Visualizing early steps in endosomal maturation

Visualizing early steps in endosomal maturation ...

Poxvirus Gene Accordions

Nels Elde describes how poxviruses utilize gene "accordions" to increase the sampling potential for mutations in a small number of genes, revealing a new mode of virus adaptation....

Rigor Mortis in C. elegans Organismal Death / Cell Reports, March 6, 2018 (Vol. 22, Issue 10)

Rigor Mortis in C. elegans Organismal Death / Cell Reports, March 6, 2018 (Vol. 22, Issue 10) ...