Establishing Robust Left-Right Asymmetry in the Vertebrate Embryo
Establishing Robust Left-Right Asymmetry in the Vertebrate Embryo - Tetsuya Nakamura discusses the role of a Nodal-Lefty-based reaction-diffusion system in generating left-right asymmetry in the mouse...
Gene Discovery in Mendelian Brain Disorders - A Center for Mendelian Genomics gene discovery study is presented that utilizes genomic approaches, which detect rare variant—single nucleotide variants (...
Regulation of EMT in Breast Cancer Cells by Cell Contact and Adhesion
Regulation of EMT in Breast Cancer Cells by Cell Contact and Adhesion - In this video abstract, the authors discuss their article "Regulation of Epithelial-Mesenchymal Transition in Breast Cancer...
How Attenuated Viruses Become Virulent / Cell, March 23, 2017 (Vol. 169, Issue 1)
How Attenuated Viruses Become Virulent. In this issue’s Video Abstract, Raul Andino describes the evolutionary strategies by which vaccine strains can become pathogenic, and provides a framework for r...
A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons. Efficient retrograde access to projection neurons for the delivery of sensors and effectors constitutes an important a...
Video Highlight: Author Aristea Binia on her recently published Human Mutation paper entitled "A Polymorphism Affecting MYB Binding Within the Promoter of th......
Ken Cadwell and colleagues demonstrate that the bacterial sensor Nod2 prevents intestinal inflammation by regulating the intestinal microbiota, particularly the expansion of Bacteroides vulgatus, a co...
Martha Giraldo, a research associate in the Department of Plant Pathology, was recently recognized for her innovative use of electronic media in her doctoral dissertation. She is one of three recipien...
Liam Redgrave, Sam Sutton, Mark Webber, and Laura Piddock discuss bacterial resistance to fluoroquinolones. They explore how fluoroquinolones target bacterial type II topoisomerases to interfere with ...
Friedhelm Hildebrandt describes how whole-exome resequencing of individuals with ciliopathies reveals mutations in DNA damage response genes, suggesting new pathogenic mechanisms behind this class of ...
Bioluminescent millipedes - Bioluminescence is the ability of an organism to generate its own light. Numerous functions have been proposed for the 40 or more independent origins of bioluminescence, fo...
