The basal ganglia are critical for movement generation and value-based decisions, but while a contribution to perceptual decisions has been suggested, strong support for this proposal is lacking. Here...
Aneuploidy via Telomere Attrition - Telomere dysfunction and aneuploidy are both common features of cancer cells. But are they causally linked? Watch and listen as Titia de Lange and Teresa Davoli tak...
Developmental milestones punctuate gene expression in the Caenorhabditis embryo. A fundamental question in developmental biology relates to the connection between morphological stages and their underl...
How Endogenous Opioids Control Pain Sensitivity. A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins. Pain thresholds are, in part, set as a function of e...
Watching Inhibitory Synapses Remodel - By simultaneously monitoring in vivo synapse and dendritic spine dynamics in adult mammalian cortical pyramidal cells, Elly Nedivi and colleagues provide new ins...
Signal Spreading from a Single Synapse. Researchers from Max Planck Florida Institute for Neuroscience revealed signal spreading during structural plasticity of dendritic spines using new biosensors....
