Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation Jonathan Sebat and colleagues explain how they tested their hypothesis that hypermutability is a property of genes implicated in autism spectrum disorders (ASD). The authors used whole-genome sequenci... Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle Erica Saphire and colleagues describe the remarkable plasticity demonstrated by the Ebola VIRUS protein VP40, which undergoes at least three distinct structural conformations to carry out different fu... TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets Lily Jan and colleagues describe their work using TMEM16F knockout mice to discover the mechanism of lipid scrambling at the plasma membrane, an important precursor step in platelet activation during ... Created and maintained by Ryan Watkins (2013-present)
Biology
Biology
Biology