Figure360: Trends in Cancer, Rozhok et al., Figure 2
Figure360: Trends in Cancer, Rozhok et al., The Armitage–Doll multistage model of carcinogenesis refocused cancer science by postulating that carcinogenesis is driven by a sequence of genetic changes ...
Human Mutation - Yuehua Zhang, Liping Wei, and colleagues
Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo” SCN1A Mutations in Children with Dravet Syndrome. The majority of children with Dravet syndrome (DS) are caused b...
How to Undress an mRNP - Nonsense-mediated mRNA decay requires the RNA helicase Upf1, but as Jens Lykke-Andersen and colleagues explain, Upf1 does more than unwind RNA. It also strips off the mRNA's p...
Multitasking microRNA regulates metastasis - Understanding how a tumor switches from sustaining growth in just one part of the body to disseminating secondary tumors throughout the body, a process cal...
In this video, Josselyn and colleagues summarize their findings on how neurons are chosen (or allocated) to be part of a memory engram. For more information, see Yiu, Mercaldo et al., Neuron 83(3), ht...
Pancreatic Beta Cell Dedifferentiation as a Mechanism of Diabetic Beta Cell Failure
Domenico Accili challenges a prevalent view that pancreatic Beta cells undergo apoptosis in conditions that induce diabetes, suggesting instead that dedifferentiation is a major mechanism of Beta cell...
Complete Growth Cone Response to a Concanavalin-A-Coated Microneedle
Complete Growth Cone Response to a Concanavalin-A-Coated Microneedle - An Aplysia growth cone advances in response to a concanavalin-A-coated microneedle. Bottom: the temporal profile of traction forc...
De Novo Coding Variants Are Strongly Associated With Tourette Disorder
De Novo Coding Variants Are Strongly Associated With Tourette Disorder. New research led by UC San Francisco scientists Jeremy Willsey and Matthew State has identified four likely risk genes with mult...
