TRPA1 Gain of Function Linked to Human Pain - Mutations in ion channels underlie multiple neurological disorders, including pathological pain states. Although previous work with knock-out mice has sug...
Experimental observation of long-term memory formation and retrieval in vertebrate brain has long been an elusive goal. Here, Aoki et al. subject zebrafish to a reinforcement learning task and study n...
Building Stem Cell Niches from Scratch - Thomas Boehm and Lesly Calderón decode the rules of stem cell recruitment by reverse engineering the thymic niche....
A Novel Analgesic Isolated from a Traditional Chinese Medicine
Research conducted through a collaboration between scientists at the University of California, Irvine (UCI) and the Chinese Academy of Sciences (CAS) has identified a compound within the plant Corydal...
Cell Surface Topography Is a Regulator of Molecular Interactions
A neutrophil labeled with Alexa-488-conjugated anti-L-selectin spreads onto and engulfs an IL-8-coated glass bead in bright field, epifluorescence, and TIRFM. See the paper by Lomakina et al. in the S...
In this video abstract, Schobel et al. describe progressive functional and structural abnormalities of the hippocampus observed in MRI studies of patients who progress to psychosis and mice exposed to...
In this video, Ira Espuny-Camacho and Pierre Vanderhaeghen describe how human pluripotent stem cells can be turned into cortical pyramidal neurons, mimicking key aspects of human corticogenesis. Most ...
Where and How Is Motor Memory Stored?/Cell October 27, 2016 (Vol. 167, Issue 4)
Where and How Is Motor Memory Stored?/Cell October 27, 2016 (Vol. 167, Issue 4) - Have you ever wondered why you lost appetite when sick? Maybe it is your body's way to tell you not to eat certain foo...