Spatial and Temporal Dynamics of the AMPA Receptor Proteome
Spatial and Temporal Dynamics of the AMPA Receptor Proteome. Native AMPA receptors are macromolecular complexes assembled from a total of more than 30 different constituents that determine architectur...
Phase Transition in Disease/ Cell August 27, 2015 (Vol. 162, Issue 5)
Phase Transition in Disease/ Cell August 27, 2015 (Vol. 162, Issue 5) - In this video and the accompanying Cell paper, the Tony Hyman and Simon Alberti groups at Max Planck Institute propose an intere...
Neocortical Neuronal Ensembles - Firing in neocortical networks appears to be dominated by a small population of highly active neurons. In this video abstract, Alison Barth and colleagues describe the...
Antibiotic Adjuvants / Trends in Microbiology October 2016 (Vol. 24 Issue 10)
Antibiotic Adjuvants / Trends in Microbiology October 2016 (Vol. 24 Issue 10) - Rooted in the mechanism of action of antibiotics and subject to bacterial evolution, antibiotic resistance is difficult ...
What Makes an Osteoclast Special? - Hiroshi Takayanagi, discusses how he decided at the time to investigate the transcriptional effectors of osteoclast RANKL signaling, within Tadatsugu Taniguchi's gr...
Plasmodium Sporozoites Form Transient Vacuoles during Cell Traversal
Plasmodium Sporozoites Form Transient Vacuoles during Cell Traversal - Spinning disk confocal microscopy of HepG2 cells expressing a fluorescent marker of the plasma membrane, N20-mCherry, showing egr...
Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
Eric Rubin and colleagues describe how tuberculosis bacteria undergo metabolic adaptation to survive attempts by CD4 T cells to starve them of tryptophan. They identify a small-molecule inhibitor of t...
Complete Growth Cone Response to a Concanavalin-A-Coated Microneedle
Complete Growth Cone Response to a Concanavalin-A-Coated Microneedle - An Aplysia growth cone advances in response to a concanavalin-A-coated microneedle. Bottom: the temporal profile of traction forc...