Scattering of Cell Clusters in Confinement - Epithelial-to-mesenchymal transition (EMT) enables scattering of cell clusters and disseminates motile cells to distant locations in vivo during embryonic ...
What Makes an Osteoclast Special? - Hiroshi Takayanagi, discusses how he decided at the time to investigate the transcriptional effectors of osteoclast RANKL signaling, within Tadatsugu Taniguchi's gr...
Cell-Type-Specific Sensorimotor Processing in the Striatum
Cell-Type-Specific Sensorimotor Processing in the Striatum - Carl Petersen describes whole-cell recordings from striatal projection neurons in behaving mice carried out by Tanya Sippy, and optogenetic...
We’ve all heard the expression “monkey see, monkey do", but actually, that's a myth. Imitation is very rare in the animal kingdom. Apes can imitate sometimes, but – apart from humans – the animal...
Sensing DNA Damage, ATP Orders an Mre11-Rad50 Clamp Down
Sensing DNA Damage, ATP Orders an Mre11-Rad50 Clamp Down - By trapping Mre11-Rad50 in mulitple states, Karl-Peter Hopfner and colleagues discover that Mre11-Rad50 transiently assembles into an ATP-con...
Revitalizing Our View of Heart Development - Robert Kelly discusses the historical context for the work, outlines how research into the second heart field has progressed in the interim, and highlights...
Clock and Wavefront Model for Vertebrate Segmentation
Clock and Wavefront Model for Vertebrate Segmentation - This model proposes that the production of somites during embryogenesis results from a molecular oscillator (called the clock) traveling along t...
Removing Stressed Mitochondria from Axons Independent of Mitophagy
Removing Stressed Mitochondria from Axons Independent of Mitophagy. Lin and Cheng et al. reveal a new mechanism maintaining axonal mitochondrial integrity by releasing anchoring protein syntaphilin fr...
How to Inflame Cancer Growth / Cell, July 13, 2017 (Vol. 170, Issue 2)
How to Inflame Cancer Growth. Cancer cells are surrounded by normal cells like fibroblasts and immune cells, but can they be corrupted to promote growth of a tumor? In this video abstract, Andy Minn a...
The Function and Organization of the Fly Flight Motor/ Curr. Biol., Jan. 26, 2017 (Vol. 27, Issue 3)
The Function and Organization of the Fly Flight Motor/ Curr. Biol., Jan. 26, 2017 (Vol. 27, Issue 3). Fruit flies execute agile aerial maneuvers using only twelve control muscles per wing. In this stu...