Decoding Attention from Prefrontal Neuronal Ensembles
Decoding Attention from Prefrontal Neuronal Ensembles - This video provides evidence of the role of the primate lateral prefrontal cortex on allocating covert attention. The authors demonstrate that t...
Sequential and Rhythmic Production of Somites - Illustrated with the developing zebrafish embryo, somitogenesis is a sequential and rhythmic process that subdivides the mesoderm of the vertebrate embr...
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Robert Siliciano and colleagues talk about their latest findings showing that the number of HIV proviruses in the latent reservoir is greater than previously thought, underscoring the need to re-evalu...
Meiotic Nuclear Oscillations Are Necessary to Avoid Excessive Chromosome Associations. Pairing of homologous chromosomes is a crucial step in meiosis, which in fission yeast depends on nuclear oscilla...
Cadherin Control of Dendrite Number - Dendrites vary widely in number and organization across types of neurons. Lisa Goodrich and colleagues investigate the mechanisms that define dendrite number in r...
Breaking Bcr-Abl Resistance - Giulio Superti-Furga discovers a new vulnerability of drug-resistant Bcr-Abl mutants—blocking their SH2 domain interface enhances the effectiveness of tyrosine kinase inh...
Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer
Richard Gregory and colleagues reveal that the Hippo-signaling pathway and its downstream target YAP regulate miRNA biogenesis in a cell-density-dependent manner, which may be responsible for the wide...
Experimental observation of long-term memory formation and retrieval in vertebrate brain has long been an elusive goal. Here, Aoki et al. subject zebrafish to a reinforcement learning task and study n...