Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties Florian Greten and colleagues explain why enhanced Wnt signaling causes postmitotic (non-stem) cells to dedifferentiate and reacquire stem cell characteristics, enabling the cells to initiate tumorige... The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation Ron Germain and colleagues identify the mitochondrial adapter molecule MAVS as a critical regulator of inflammasome activation. They discuss their findings on how MAVS and another adapter, ASC, are bo... Created and maintained by Ryan Watkins (2013-present)
Biology
Biology